5-aminolevulinic acid-guided surgery for focal pediatric brainstem gliomas: A preliminary study
نویسندگان
چکیده
منابع مشابه
Focal brainstem gliomas
ةيلمعلا ءانثأ ريوصتلا كلذكو ةروطتلما ةيبصعلا ةحلالما ةمظنأ حارج ةردق نم تززع ةيبصعلا ةيجولويزيفلا دصرلا ايجولونكتو يفو ،ةيرؤبلا غامدلا عذج ماروأ لاصئتسا نم باصعلأاو خلما هذه .ةحارجلل ةلباق ريغ ةرشتنلما غامدلا عذج ماروأ ربتعت لباقلما ،ينثحابلا سفنل اًقباس ترشن ةساردل ًارارمتسا ةيملعلا ةقرولا .غامدلا عذج ماروأ ريوصت اضيأو فينصتو صيخشت تشقان عذج ماروأ ةحارج بيلاسأو قرط نافلؤلما حرشي ةلاقلما هذه يف ء...
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The need for novel, effective, and safe treatments for malignant glioma is obvious. Despite surgery, radiotherapy, and chemotherapy, the median survival time of patients with glioblastoma multiforme (World Health Organization Grade IV) still does not exceed 15 months. Patients with anaplastic astrocytoma (World Health Organization Grade III) have a slightly better prognosis. As a result of the ...
متن کاملRandomized, Prospective Double-Blinded Study Comparing 3 Different Doses of 5-Aminolevulinic Acid for Fluorescence-Guided Resections of Malignant Gliomas
BACKGROUND Five-aminolevulinic acid (5-ALA) is used for fluorescence-guided resections of malignant glioma at a dose of 20 mg/kg; yet, it is unknown whether lower doses may also provide efficacy. OBJECTIVE To perform a double-blinded randomized study comparing 3 different doses of 5-ALA. METHODS Twenty-one patients with suspected malignant glioma were randomly assigned to 0.2, 2, or 20 mg/k...
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This report aims to evaluate the usefulness of 5-aminolevulinic acid (5-ALA) fluorescence-guided Mohs surgery resection of penile-scrotal extramammary Paget's disease for achieving maximum tumor resection. Between January 2014 and December 2015, 5 patients underwent surgical resection of a penile-scrotal extramammary Paget's disease in department of urology, Huashan hospital, Fudan University. ...
متن کاملFluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial.
BACKGROUND 5-Aminolevulinic acid is a non-fluorescent prodrug that leads to intracellular accumulation of fluorescent porphyrins in malignant gliomas-a finding that is under investigation for intraoperative identification and resection of these tumours. We aimed to assess the effect of fluorescence-guided resection with 5-aminolevulinic acid on surgical radicality, progression-free survival, ov...
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ژورنال
عنوان ژورنال: Surgical Neurology International
سال: 2020
ISSN: 2152-7806
DOI: 10.25259/sni_246_2020